Протитуберкульозні та протигрибкові ЛЗ(відповідь одразу)

A 50-year-old man comes to the physician because of a persistent cough for the past 2 months. He has had a 5-kg (11-lb) weight loss during this period. He is a poultry farmer. Current medications include atenolol, enalapril, hydrochlorothiazide, and omeprazole for hypertension and gastroesophageal reflux. Physical examination shows no other abnormalities. Laboratory studies show histoplasmosis infection. Itraconazole therapy is initiated and omeprazole is discontinued. Which of the following best describes the reason for removing omeprazole from this patient's medication regimen?

An 18-year-old patient has developed candidiasis after the case of pneumonia treated with β-lactam antibiotic. What antimycotic agent should be prescribed?

A patient suffering from invasive aspergillosis is firstadministered NSAIDs, antihistamines, and adrenal glucocorticoids prior to administration of an antifungal drug. The antifungal drug works by

Which one of the following drugs is most suitable in an immunocompromised patient for prophylaxis against infection due

to Cryptococcus neoformans?

A patient was diagnosed with active focal pulmonary tuberculosis. What drug should be prescribed in the first place?

After 4 months of treatment for tuberculosis the patient began complaining of toes and fingers numbness, sensation of creeps. He was diagnosed with polyneuritis. What antituberculous drug might have caused these complications?

A patient diagnosed with focal tuberculosis of the upper lobe of the right lung had been taking isoniazid as a part of combination therapy. After some time, the patient reported of muscle weakness, decreased skin sensitivity, blurred vision, impaired motor coordination. Which vitamin preparation should be used to address these phenomena?

A patient with pulmonary tuberculosis is prescribed the most effective antituberculous antibiotic. Name this drug:

A patient is prescribed Isoniazid prophylactically since another family member currently has tuberculosis. When the patient ends up getting tuberculosis despite prophylaxis, resistance to isoniazid is suspected. In what way did this resistance likely develop?

A 35-year-old man under the treatment for pulmonary tuberculosis has acute-onset of right big toe pain, swelling, and low-grade fever. The gouty arthritis was diagnosed and high serum uric acid level was found. Which of the following antituberculosis drugs are known for causing high uric acid levels?

A patient suffers from pulmonary tuberculosis. During treatment neuritis of visual nerve arose. What drug has caused this by-effect?

A 63-year-old woman comes to the physician because of a 2-week history of fatigue, malaise, nausea and vomiting, and decreased appetite; these symptoms have worsened during the past week. She was diagnosed with tuberculosis 3 months ago; a multidrug regimen was initiated at that time. Her temperature is 37.1°C (98.8°F). Physical examination shows scleral icterus and tenderness over the right upper quadrant of the abdomen; there is no hepatomegaly. Serum studies show a total bilirubin concentration of 6.5 mg/dL, AST activity of 580 U/L, and ALT activity of 650 U/L. Which of the following drugs is the most likely cause of these findings?

A patient with pulmonary tuberculosis is prescribed the most effective antituberculous antibiotic. Name this drug:

After starting the treatment for pulmonary tuberculosis, the patient came to a doctor with complaints of tears and urine becoming red-colored. What drug has caused these changes?

The causative agent of tuberculosis can exist both intracellularly and extracellularly, as well as in caseous necrosis. What drug can have a harmful effect on Mycobacterium tuberculosis of any localization?

A 45-year-old patient, who was prescribed complex therapy by a dentist due to recurrent aphthous stomatius, developed an imbalance of the oral cavity microbiota with an increased amount of yeast fungi. What drug should be prescribed to this patient?

A patient diagnosed with oral candidiasis was prescribed an antifungal drug. What drug was preseribed for this patient?

Following the treatment with anti-tuberculosis drugs, a 48-year-old woman developed optic nerve neuritis, memory. impairment, and seizures. What anti-tuberculosis drug was she taking?