Антибіотики

To treat bronchitis the patient was prescribed a beta-lactam

antibiotic. Its mechanism of action is based on inhibition of murein

production, which results in death of the causative agent. Name

this drug:

A patient with bacterial pneumonia was prescribed

Benzylpenicillin. What is the mechanism of its antibacterial effect?

Treatment course of bacterial pneumonia included Benzylpenicillin sodium salt. What is the mechanism of its antimicrobial action?

A 19-year-old woman suffers from primary syphilis. Doctor

administered her complex therapy that includes Benzylpenicillin

sodium salt. What is the mechanism of action of this drug?

A 5-year-old child has been diagnosed with acute right distal

pneumonia. Sputum inoculation revealed that the causative agent

is resistant to penicillin, but it is senstive to macrolides. What drug

should be prescribed?

A patient underwent appendectomy. In the postoperative period

he has been taking an antibiotic. The patient complains about

hearing impairment and vestibular disorders. What group of

antibiotics has such by-effects?

A patient suffers from severe postoperative pseudomonadous

infection. What of the following antibiotics should be administered

in this case?

Mother of a 2-year-old child was consulted by a stomatologist. In

the period of pregnancy, she was irregularly taking antibiotics for

an infectious disease. Examination of the child revealed incisor

destruction, yellow enamel, brown rim around the dental cervix.

What drug has apparent teratogenic effect?

A 26-year-old female patient with bronchitis has been

administered a broad spectrum antibiotic as a causal treatment

drug. Specify this drug:

Administration of Doxycycline hydrochloride caused an imbalance

of the symbiotic intestinal microflora. Specify the kind of

imbalance caused by the antibiotic therapy:

A patient with streptococcal infection of the gingiva was

prescribed a drug with β-lactam ring in its structure. What drug of

those listed below belongs to this pharmacological group?

Patient was admitted to the infection unit with diagnosis of

bacterial dysentery. On laboratory studies it was revealed that

causative element is sensitive to the many antimicrobial

medicines, but patient has anemia. What medicine is

contraindicated to the patient?

An 82-year-old hospitalized patient with creatinine clearance of 25

ml/min has a microbial infection requiring treatment with

antibiotics. Which of the following drugs is least likely to require a

dosage adjustment, either a smaller dose than usual or an

increased interval between doses?

In bacterial meningitis, third-generation cephalosporins are

commonly drugs of choice. However, in neonatal meningitis they

would not provide coverage if the infection was due to which of

the following organisms?

A 7-year-old child presents with pharyngitis and fever of 2 days’

duration, and microbiology reveals small, translucent, beta-

hemolytic colonies sensitive in vitro to bacitracin. Past history

includes a severe allergic reaction to amoxicillin when used for an

ear infection. The physician needs to treat this infection, but

prefers not to use a drug that needs parenteral administration.

Which one of the following agents is most likely to be appropriate

in terms of both effectiveness and safety?

What antibiotic effectively treats a variety of causative organisms

for bacterial pneumonia, and also works at the 50S ribosomal

subunit?

Which one of the following drugs inhibits bacterial protein

synthesis, preventing the translocation step via its interaction with

the 50S ribosomal subunit?

Gentamicin would be an ineffective drug for which of the following

organisms?

In a patient who has an established hypersensitivity to

metronidazole, what is the most appropriate drug to use for the

management of pseudomembranous colitis?

Mother of a 2-year-old child made an appointment with the

dentist. She complains of teeth destruction in her child.

Examination shows that the milk teeth of the child are deformed,

carious, and have a brown border at their cervices. Medical history

of the mother revealed that during her pregnancy she had been

taking antibiotics without the doctor’s prescription. What group of

antibiotics with the most marked teratogenic effect was likely

taken by the mother?

A patient with streptococcal infection of the gingiva was

prescribed a drug with β-lactam ring in its structure. What drug of

those listed below belongs to this pharmacological group?

The mother of a 2-year-old child came to the dentist.

During her pregnancy she was randomly taking antibiotics

to treat an infectious disease. Examination of the child

revealed destruction of the incisors, yellow enamel, and a

brown border near the dental cervices. What medicine has

a marked teratogenic effect?

A 70-year-old man is brought to the emergency department by his

wife because of fever and shortness of breath for 2 days. He

underwent an oral surgical procedure 6 weeks ago. His

respirations are 22/min, and blood pressure is 140/60 mm Hg. A

soft diastolic murmur is heard. The diagnosis of bacterial

endocarditis is made. Gentamicin therapy is initiated. This patient

is at increased risk for developing which of the following as a

result of this therapy?

Prescription of penicillin G sodium salt has caused development of

neurotoxic effects (hallucinations, convulsions). Such reaction is

the result of antagonism with the following neurotransmitter:

To treat bronchitis the patient was prescribed a beta-lactam

antibiotic. Its mechanism of action is based on inhibition of murein

production, which results in death of the causative agent. Name

this drug:

A 5-year-old child has been diagnosed with acute right distal

pneumonia. Sputum inoculation revealed that the causative agent

is resistant to penicillin and senstive to macrolides. What drug

should be prescribed?

A patient with streptococcal infection of the gingiva was

prescribed a drug with β-lactam ring in its structure. What drug of

those listed below belongs to this pharmacological group?

A 4-year-old child presents with numerous carious cavities and

yellow-colored teeth. The mother has a history of antibiotic

treatment during her pregnancy. What antibiotic was the most

likely taken by the child’s mother?

S. aureus can cause various infections from purulent complications of wounds to

pneumonia and sepsis. Why is penicillin therapy of staphylococcal infections not

very effective?

Antibiotics (streptomycin, erythromycin, chloramphenicol) are used to treat

infectious bacterial diseases. What stage of protein synthesis in the microbial cell

do they inhibit?

A 30-year-old woman was hospitalized with the diagnosis of primary syphilis.

What drug should be prescribed for this patient?

A 22-year-old woman came to a dermatologist with complaints of a purulent rash

on her face and back. Her medical record indicates a H.pylori infection. Taking into

account this concomitant pathology, the doctor prescribed her an antibacterial drug

that would be effective both against the pathogens of soft tissue infections and

against H.pylori. What antibacterial drug did the doctor prescribe?

What drug is a beta-lactam antibiotic?

A patient has undergone appendectomy. During the postoperative period, the

patient was receiving an antibiotic. After a short while, the patient developed

complaints of hearing impairment. What group of antibiotics has characteristic side

elfects that manifest as hearing impairment and damage to the vestibular apparatus?